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The Optogenetics APP What is the Optogenetics APP? The Optogenetics APP is a tool to aid an investigator in
estimating the required optical power for a given in-vivo experiment
involving optogenetics or any other experimental approach that includes light
delivery to deep brain areas via optical fibers. Different brain areas have different optical properties, which
determine how light scatters and distributes (and how deeply it penetrates
the tissue), once it exits the fiber. The APP has a complete mouse brain
atlas included that can be used to determine the optical properties of any
brain area in the mouse brain. A user finds the brain areas of choice, marks
it on the atlas, then tell the APP what type of optogenetic protein he/she
wants to use, as well as the type of optical fiber, desired optical power,
and desired protein activation ratio. Based on these parameters, the APP estimates how far the light
will spread in this particular experimental situation (and thus, up to which
distance from the fiber tip optogenetic protein activation can be expected). For a detailed description of the underlying experimental data,
the experimental approach, and an explanation of the optical equations,
please see the following peer-reviewed journal article: Al-Juboori et al: Light scattering properties differ between different areas of
the adult mouse brain. PlosONE, publication e67626, published July 9, 2013. This manuscript is open access (i.e. can be downloaded free of
charge through the link shown above). How do I get the Optogenetics APP? The application is
currently available for iOS and Android. iOS: Compatible with iPhones, iPads, and certain iPods.: Download
Optogenetics (the demo version) from iTunes Download
Optogenetics Pro (the full version) from iTunes Android : Compatible with Android phones and tablets: Download
Optogenetics (the demo version) from Google Play Store Popneuron Limited 3700 Quebec Street Unit 100-121 Denver, CO 80207-1639 U.S.A. www.popneuron.com info@popneuron.com |